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LT Barclay

(3,057 posts)
Sun Jul 20, 2025, 01:09 AM Jul 20

Need information I can trust- wife is on 3rd round of chemo wants to try invermectin

I'll try to keep this post short.
My wife:
Diagnosed with 2 types of breast cancer and CLL in 2019 when she was 53.
Double mastectomy and chemo.
Something wrong with chemo port causing 5 infections resulting in sepsis and endocarditis that destroyed aortic valve, requiring valve replacement and then pacemaker defibrillator.
First recurrence of cancer, requiring radiation and chemo.
Replacement of first heart valve due to stenosis from radiation.
We are now in second recurrence of cancer and third round of chemo. This is supposed to be more targeted, but has caused her severe diarhhea, leading to multiple UTIs, and then pleural effusion requiring more hospitalizations.
At this point the blunt way of putting things is the oncologist is saying it is either chemo or cancer.
My wife is being steered to invermectin by her sweet but wing-nut aunt because she is being destroyed by the chemo and feels she has no life as leaving the house is difficult.
I don't know what to say to her. Is there any harm to trying it?

28 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
Need information I can trust- wife is on 3rd round of chemo wants to try invermectin (Original Post) LT Barclay Jul 20 OP
Is this a joke? NO! not Ivermectin. If I was in your wife's condition I would use marijuana. The internet has info in2herbs Jul 20 #1
I wish it was a joke. Her aunt is telling her that this will stop the cancer. LT Barclay Jul 20 #5
Did a quick search at national cancer institute Lifeafter70 Jul 20 #2
Sorry to hear that. My wife has been reading a book called "Chris Beat Cancer" but hasn't been able to realistically LT Barclay Jul 20 #6
There are so many cancer diets out there Lifeafter70 Jul 20 #10
very sorry for what she is going through Skittles Jul 20 #3
I agree, but she's at a desperate place LT Barclay Jul 20 #7
IP-6 PikaBlue Jul 20 #4
Thanks LT Barclay Jul 20 #8
This message was self-deleted by its author pbmus Jul 20 #9
Thanks. That is a good start and I'll have to dig more. I'm really skeptical because since Trump promoted it, there is LT Barclay Jul 20 #12
Thank you for posting this Lifeafter70 Jul 20 #14
so Skittles Jul 20 #15
This message was self-deleted by its author pbmus Jul 20 #16
yeah OK Skittles Jul 20 #17
Immuneothrapy trials Donman Jul 20 #11
I'm a PT and I realized I've been sitting on the sidelines too much as I believed what she's been experiencing are LT Barclay Jul 20 #13
What your wife needs from you right now, money cannot buy. Irish_Dem Jul 20 #18
Thanks. I'm very angry at work because I haven't been able to be there with her during appointments and even when I LT Barclay Jul 20 #19
The important thing is that she knows you have her back, and love her, support her. Irish_Dem Jul 21 #20
Fundamentally, ivermectin is for parasites Sparkly Jul 23 #21
Thanks. I'm leery of it because it has achieved miracle cure status among the Trump followers and so any source LT Barclay Jul 23 #22
Sugar Sparkly Monday #23
Surprisingly, in the scientific literature the use of ivermectin in breast cancer has been discussed in concert... NNadir Yesterday #24
Thanks. My wife is HER +. Her oncologist did say that the CART-T therapy is starting to be used on hard tumors and LT Barclay 20 hrs ago #25
I'm so sorry to hear about your wife's and your situation Bayard 19 hrs ago #26
Thanks so much. We have a golden retriever puppy who is quite protective after seeing my wife fall. And parakeets. I LT Barclay 16 hrs ago #27
Awww....good pupster! Bayard 9 hrs ago #28

in2herbs

(3,860 posts)
1. Is this a joke? NO! not Ivermectin. If I was in your wife's condition I would use marijuana. The internet has info
Sun Jul 20, 2025, 01:16 AM
Jul 20

and most MJ stores are helpful.

LT Barclay

(3,057 posts)
5. I wish it was a joke. Her aunt is telling her that this will stop the cancer.
Sun Jul 20, 2025, 01:42 AM
Jul 20

She was using medical marijuana, but we are in a state now where it is not available. We had hoped to have a better quality of life here, but she has trouble doing anything. I'm working on trying to find a good time for a trip to the coast so we can get there and she can rest before trying some light activities.

Lifeafter70

(598 posts)
2. Did a quick search at national cancer institute
Sun Jul 20, 2025, 01:27 AM
Jul 20

I was surprised to learn it is being used along with chemo in some trials for triple negative breast cancer. It is only in trials and not fda approved. It has shone promise in inhibiting cancer cell growth.
I would talk to her oncologist in regards to this and not take her aunts word that it works.
Cancer sucks my son has been fighting acc cancer since 2016. He just had his third recurrence and was told there are no treatments available. Unfortunately chemo has no effect on his type of cancer.
Sending positive vibes your way.

LT Barclay

(3,057 posts)
6. Sorry to hear that. My wife has been reading a book called "Chris Beat Cancer" but hasn't been able to realistically
Sun Jul 20, 2025, 01:44 AM
Jul 20

follow any of the diet suggestions.

Lifeafter70

(598 posts)
10. There are so many cancer diets out there
Sun Jul 20, 2025, 02:02 AM
Jul 20

The best one we have come up with is to eat healthy lol. Protein, veggies and fruits. He trys to stay away from processed food and surgar. His cancer travels along his nerves, is microscopic and slow growing. That is why it is so difficult to treat. Many with acc survive 10 to 15 years after being diagnosed.
I would ask your wife's oncologist about those trials. Stay supportive for her but take her docs advice.

Skittles

(166,341 posts)
3. very sorry for what she is going through
Sun Jul 20, 2025, 01:29 AM
Jul 20

but do NOT take medical advice from anyone but medical professionals

PikaBlue

(361 posts)
4. IP-6
Sun Jul 20, 2025, 01:34 AM
Jul 20

Do a quick Google search for "IP-6 and breast cancer". Then discuss with your wife's physician.

Response to LT Barclay (Original post)

LT Barclay

(3,057 posts)
12. Thanks. That is a good start and I'll have to dig more. I'm really skeptical because since Trump promoted it, there is
Sun Jul 20, 2025, 02:09 AM
Jul 20

a cult status around it and as far and I can tell there are people who will claim it can cure damn near anything (I have one as a patient).

Lifeafter70

(598 posts)
14. Thank you for posting this
Sun Jul 20, 2025, 02:16 AM
Jul 20

I did a quick search and found the clinical trials but couldn't post the link. So many are dealing with different types of cancer that do not respond to chemo or radiation and are desperate for treatment that promise to relieve their pain. Unfortunately many are just quacks looking to make a buck.
I want to thank you for the laugh in regards to your disclaimer.

Skittles

(166,341 posts)
15. so
Sun Jul 20, 2025, 02:43 AM
Jul 20
There is no conclusive evidence from human clinical trials demonstrating ivermectin’s efficacy or safety as a cancer treatment.

Ivermectin is not currently considered safe or effective for cancer treatment

that and being pimped by rightwing hacks makes it suspect

Response to Skittles (Reply #15)

Donman

(29 posts)
11. Immuneothrapy trials
Sun Jul 20, 2025, 02:08 AM
Jul 20

Check for trials of immuneunotherapy. Check to see if blood coagulates properly. It's a shame that the port was such a problem. Do the best to maintain proper weight. If you can find a good homeopathic doctor, they can help with supplements. NO IVERMECTINE.
ATTITUDE is important and daily breathing and physical exercise if it is possible. Wishing you the best from the bottom of my heart. I've been close to this before. It's tough but try to keep to the sunnyside, as it's been said. AVOID SUGAR.

LT Barclay

(3,057 posts)
13. I'm a PT and I realized I've been sitting on the sidelines too much as I believed what she's been experiencing are
Sun Jul 20, 2025, 02:13 AM
Jul 20

related to the cancer not other causes. Now I'm trying to get in the game and keep her active and trying to help her control the lymphedema. I just bought her a new exercise machine, and an AC unit for the sunroom to give her exercise and more space in the house. If I had the money now, my goal is to recreate our yard like a mini botanical garden. I'm only about 100k short at the moment.

Irish_Dem

(72,738 posts)
18. What your wife needs from you right now, money cannot buy.
Sun Jul 20, 2025, 05:44 AM
Jul 20

It is not about a $100K fancy garden.

It is about your devotion, love, support, time, active involvement in her health and treatment.
Connecting with her, spending quality time together. Helping her fight and heal if possible.

Asking questions for her, talking to medical providers, exploring options for her.
Small but important things like turning the sunroom into a healing and exercise spot for her.

She has descended into the severe illness nine circles of hell and needs as much help, support,
love that you can muster, and she needs to know you have her back and are in her corner.

LT Barclay

(3,057 posts)
19. Thanks. I'm very angry at work because I haven't been able to be there with her during appointments and even when I
Sun Jul 20, 2025, 11:35 PM
Jul 20

qualify for FMLA, it would be a real financial burden if they start docking my pay. Even though I have to work extra hours anyway, they will claim it is my fault for not completing documentation during the day, even though I have to see 2-3 patients at a time as a Physical Therapist and their EMR is crappy and slow.
The garden is to give her a peaceful place and I keep trying to find small things to make her smile and enjoy life. I do give her all the time I can.

Irish_Dem

(72,738 posts)
20. The important thing is that she knows you have her back, and love her, support her.
Mon Jul 21, 2025, 05:12 AM
Jul 21

She knows this even when you are away working.
So going to appointments is not critical.

People can find a peaceful place without an expensive garden.
Bring some inexpensive plants into the sunroom. Make it her peaceful place.
Add other pretty and relaxing things, you can get some things at Walmart.
Maybe some scenes, lavender, peppermint, etc.
Relaxing music.

And you enjoy it as well.

Your anger is more than just about work.

And it is not good for you to be very angry.
Being a caregiver is a very stressful job, so you need to relax and take care of yourself too.

Sparkly

(24,704 posts)
21. Fundamentally, ivermectin is for parasites
Wed Jul 23, 2025, 12:06 AM
Jul 23

Others might have said this, but the aunt doesn't know what she is saying.

I'm on my second course of chemo (5th treatment this time) and had 25 radiation treatments -- can't have any more. I've also had 2 years of a monoclonal antibody.

Ivermectin is intended for parasites, like worms. It became 'known' as a thing for Covid-19 thanks to the MAGAt. It is not for cancer.

I hope your wife will listen to medical professionals, and hope you will take care of yourself!!

LT Barclay

(3,057 posts)
22. Thanks. I'm leery of it because it has achieved miracle cure status among the Trump followers and so any source
Wed Jul 23, 2025, 09:25 PM
Jul 23

promoting it is suspect to me. I think she'd do far better by cutting out sugar and starch.
Caring for myself has been difficult, but I do find stress relievers when I need something. Latest was a radio control batmobile (the tumbler from the Christian Bale trilogy). It's a fun diversion. And I'm starting small projects for prepping my boats for the water. I have a backlog of maintenance on my sloop so she'll have to wait for a spring launch and then I can take my wife for a sail again.
Stay strong and I pray you are in remission after treatment!

Sparkly

(24,704 posts)
23. Sugar
Mon Jul 28, 2025, 05:59 PM
Monday

You are right about that -- there is a LOT of research on cancer as a metabolic disease relating to sugar, and specifically citing Metformin as a virtual "miracle drug" for some cancers!

My blood sugar has always been weird, tending toward low (runs in my family) but wondered if it related. Doctors don't want to discuss things that are so off the proven path (and hypoglycemia has no pharmacological treatment, at least not in the US). Short of Metformin, I did find an herbal supplement called Berberine that is said to regulate blood sugar, for what it's worth.

There are several books about "starving cancer," although again, my particular doctor said, "The problem with 'starving cancer' is that you starve yourself when you really need a balanced diet!" which tells me he didn't read the studies.

NNadir

(36,218 posts)
24. Surprisingly, in the scientific literature the use of ivermectin in breast cancer has been discussed in concert...
Wed Jul 30, 2025, 01:39 PM
Yesterday

...with checkpoint inhibitors. These are forms of immunomodularity approaches to cancer treatment.

Cf. Lee et al. NPJ Breast Cancet 7 Article 22 2021

As I understand it, it would be useless in the absence of coadministration of a checkpoint inhibitor, the most famous of which is Keytruda, Pembroliumab.

However, looking at ClinicalTrials.gov, there appears to be only one clinical trial underway; it's in Los Angeles. This suggests that it's not a hot topic. It is recruiting. Apparently the mechanism is to increase accessibility of tumors to T cells.

Breast Cancer is not really a single disease. There are subtypes, the most difficult to treat being triple negative. I have recently heard that there is some progress even for this.

My sister-in-law is a 8 year survivor of HER positive; She got by with just a lumpectomy. That was the last time I looked in the literature to study breast cancer so my general knowledge of the subject may be dated. I need to emphasize that I am not a physician. Neither is your wife's aunt.

It is difficult, as I know well, "to go with the program," when "the program" is not giving a desired result. Many forms of breast cancer are curable depending on cell type and the time of discovery but some are not. Oncologists are certainly aware of the best treatment options, if in fact, the exist.

I would go with the program if it were me, and right now the program doesn't appear to include Ivermectin.

We all, I'm sure, wish you success and peace.

LT Barclay

(3,057 posts)
25. Thanks. My wife is HER +. Her oncologist did say that the CART-T therapy is starting to be used on hard tumors and
Wed Jul 30, 2025, 10:39 PM
20 hrs ago

that HER+ would be a good candidate for trials as that marker is a good target for treatment.
Right now she hasn't mentioned trying the invermectin, so I'm just going to leave things alone unless she brings it up again.

Bayard

(26,177 posts)
26. I'm so sorry to hear about your wife's and your situation
Wed Jul 30, 2025, 11:54 PM
19 hrs ago

One thing I can tell you for sure, is don't let her take Ivermectin. You're right in it being a baseless wing-nut solution among MAGAts and trump. Its livestock wormer. We use it on the horses and donkeys here twice a year just in case they've picked up any parasites in the pasture. Basically, you're feeding your horse a bit of poison, that happens to kill worms. I don't know why they decided on Ivermectin specifically, when there's many different wormers out there.

I think you're on the right track with trying to keep her as stress free as possible, and a garden is a good way to do that. But, make it an indoor one, with grow lights if necessary. House plants also make for a healthier environment with filtering bad stuff in the air, and putting out oxygen.

Do you have pets? They are really comforting, empathetic, and great as de-stressors.

Please keep us posted. Consider yourself and your wife hugged.

LT Barclay

(3,057 posts)
27. Thanks so much. We have a golden retriever puppy who is quite protective after seeing my wife fall. And parakeets. I
Thu Jul 31, 2025, 02:24 AM
16 hrs ago

also got her a Birdfy birdfeeder. I think later this year, I'll get the Birdfy birdbath. I'm just trying to find small things to make her happy as her world is getting smaller. She has an annual pass for a small petting zoo nearby.
I'm having the most difficulty with doing things without her. The kids feel trapped, but when it was her and I, we did everything together for 15 years.
Have you ever heard of Peacefull Pastures? It is a one woman donkey rescue in Cole Camp, MO. She has a lot of volunteers and 140 donkeys. When we visited, she had a colt that was rejected by it's mother and was sleeping in her bedroom at night.

Bayard

(26,177 posts)
28. Awww....good pupster!
Thu Jul 31, 2025, 10:05 AM
9 hrs ago

I have not heard of that particular rescue. Sounds like they do good work. I've had a goat living in the bathroom from time to time. Its those middle of the night bottles that are the worst part of that.

How old are your kids?

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