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Coventina

(29,716 posts)
Thu Mar 26, 2026, 03:48 PM Thursday

It Begins as a Tick Bite and Can Be Devastating. And It's Spreading.

A decade ago, Scott Curatolo-Wagemann knew of only one person stricken with a tick-borne ailment called alpha-gal syndrome — the husband of his wife’s cousin.

The list has since grown in his corner of Long Island: His sister, who was bitten this past summer, has it. So does his sister’s best friend. Then there’s the mother of a boy on his son’s baseball team. The phlebotomist at the Labcorp office where he gets blood drawn has it.

And, yes, Mr. Curatolo-Wagemann has alpha-gal, too.

Once regarded as a rarity, the disease, which involves an allergy to red meat that develops after a tick bite, has emerged as a significant health menace, with the Centers for Disease Control and Prevention estimating that as many as 450,000 people nationwide may have had it in the past 15 years. And that is probably an undercount, said Dr. Scott Commins, who helped solve the mystery of alpha-gal syndrome about two decades ago.

More recently, Dr. Commins was involved in testing, largely at random, 3,000 samples from blood donors in 10 states for alpha-gal antibodies. A forthcoming study shows that in Arkansas, Kentucky and Missouri, nearly 30 percent of samples tested positive, although that doesn’t mean that all — or even most — had allergic symptoms, he said.''''

https://www.nytimes.com/2026/03/25/nyregion/alpha-gal-meat-allergy-deaths.html?

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The planet is sick and tired of us, and is actively trying to kill us.
I don't blame it a bit!

41 replies = new reply since forum marked as read
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It Begins as a Tick Bite and Can Be Devastating. And It's Spreading. (Original Post) Coventina Thursday OP
I'm picturing herds of cows Earthrise Thursday #1
And reminding us with signs that say "Eat mor chikin." nt Ilsa Thursday #9
Can you imagine the conspiracy theorizing which would ensue if a bunch of RW/manosphere figures RockRaven Thursday #2
RFK Jr. lonely bird Thursday #11
How do i enlist on the planets side? ret5hd Thursday #3
Two of my relatives in SW Missouri have this. highplainsdem Thursday #4
My husband's got it. Amethyst Ring Thursday #5
Alton Brown has one Old Crank Thursday #10
The simplest chicken recipe I know of, which I got from my brother's mother-in-law, is baked highplainsdem Thursday #18
Had to Add DET Thursday #26
It actually started being noticed in the mid 1980's. mwmisses4289 Thursday #6
You can eat venison? That's usually a problem with this allergy. highplainsdem Thursday #16
Just know the one time I tried it a few years ago, it didn't seem to cause any issue. mwmisses4289 Thursday #21
The allergy is to all mammals. marybourg Friday #33
My daughter-in-law has it. Americanme Thursday #7
Scary for me DFW Thursday #8
Not just red meat (beef, pork, lamb) but any products made with animal fat, and cow's milk and any highplainsdem Thursday #12
That is downright frightening n/t DFW Thursday #14
My relatives in Missouri are all very much into outdoor activities - hiking, fishing, kayaking, riding. highplainsdem Thursday #15
Including stuff fried with beef tallow? DBoon Thursday #27
Tallow's mentioned on that page I linked to. highplainsdem Thursday #28
Beef tallow, lard, bacon drippings, sheep fat. mwmisses4289 Thursday #30
I'm seeing "healthy" restaurants touting their use of beef tallow DBoon Thursday #31
What makes this so unusual is that it appears to be an infectious allergy Warpy Thursday #13
No luncheon meat? What about sliced deli turkey wnylib Thursday #17
Lunchmeat and sausage made from chicken and turkey should be fine. highplainsdem Thursday #19
Good grief. Hope I never have to deal with this allergy. wnylib Thursday #20
Sorry you have to avoid so many foods. I often limit wheat as much as possible because I'll get highplainsdem Thursday #22
The first time I experienced anaphylaxis, I was too spaced out from it wnylib Thursday #24
The doctor left you alone after injecting you with 60 test allergens at once? That sounds like highplainsdem Thursday #25
The office set up was like a mill. There were several wnylib Friday #34
Thanks for explaining! I still think that first allergist you saw was incredibly irresponsible, putting highplainsdem Friday #35
I don't blame you for trying the carrot cake. wnylib Friday #37
No allergy test, but I started getting respiratory symptoms from eating wheat again highplainsdem Friday #39
The reason I asked if you had been tested is that wnylib Friday #41
Just make sure you check ingredients, as anyone living with allergies know to do. mwmisses4289 Thursday #23
Blargh--ticks buzzycrumbhunger Thursday #29
Never heard of it Bayard Friday #32
I found a Cleveland Clinic Journal of Medicine page with a map showing where AGS is most common. Link: highplainsdem Friday #36
Thanks for this Bayard Friday #38
I have had Alpha Gal for a couple of years now. mackdaddy Friday #40

RockRaven

(19,335 posts)
2. Can you imagine the conspiracy theorizing which would ensue if a bunch of RW/manosphere figures
Thu Mar 26, 2026, 04:05 PM
Thursday

like Joe Rogan, Alex Jones, etc came down with this?

Amethyst Ring

(35 posts)
5. My husband's got it.
Thu Mar 26, 2026, 04:53 PM
Thursday

No more meat except poultry. No dairy, no gluten but that's old news.

Anybody got some good chicken recipes?

Old Crank

(7,049 posts)
10. Alton Brown has one
Thu Mar 26, 2026, 06:38 PM
Thursday

A one pot with chicken shallots and garlic.
Not sure if it is on the web. It is on his book. I'm just here for the food.

Good luck.

highplainsdem

(62,066 posts)
18. The simplest chicken recipe I know of, which I got from my brother's mother-in-law, is baked
Thu Mar 26, 2026, 08:32 PM
Thursday

chicken leg quarters with the skin sprinkled with celery salt and onion powder. Bake in a foil-lined pan deep enough to hold some grease. at 350 degrees for an hour and fifteen minutes. The fat will bake out of the skin and baste the meat, which will be very juicy and tender and flavorful.

mwmisses4289

(4,142 posts)
6. It actually started being noticed in the mid 1980's.
Thu Mar 26, 2026, 05:02 PM
Thursday

A woman doctor noted several of her patients were coming in, complaining of allergic reactions to red meat. She began investigating, and it led to the discovery of the lone star tick bite being the main culprit.
I have it. It can be a pain.
For me, red meat includes beef and veal, pork, mutton and lamb. Oddly, poultry and seafood are fine, and venison.
I really, really miss being able to eat steak and beef burgers. I usually sub turkey or chicken for red meat.

mwmisses4289

(4,142 posts)
21. Just know the one time I tried it a few years ago, it didn't seem to cause any issue.
Thu Mar 26, 2026, 09:16 PM
Thursday

Beef and pork on the other hand...oy.

DFW

(60,169 posts)
8. Scary for me
Thu Mar 26, 2026, 05:41 PM
Thursday

Since red meat is taboo for me, it would be a long while before I would be diagnosed, if I had it. I assume that, like with most of these tick-borne diseases, they fester and silently grow inside the host before suddenly bursting out with devastating effect, such as with Lyme Disease.

highplainsdem

(62,066 posts)
12. Not just red meat (beef, pork, lamb) but any products made with animal fat, and cow's milk and any
Thu Mar 26, 2026, 06:45 PM
Thursday

products made with milk.

Editing to add goat's milk, too.

People with alpha gal syndrome are often less allergic to dairy than to meat.

More info here:

https://www.cdc.gov/alpha-gal-syndrome/data-research/products-containing-alpha-gal/index.html

One of my nieces and my nephew's wife both have it. Both are in their 30s, have had it a couple of years, no signs of recovery yet.

highplainsdem

(62,066 posts)
15. My relatives in Missouri are all very much into outdoor activities - hiking, fishing, kayaking, riding.
Thu Mar 26, 2026, 08:20 PM
Thursday

All of which are much riskier now.

The good news for people who have alpha-gal is that they can sometimes recover if they can go years without another tick bite.

DBoon

(24,980 posts)
27. Including stuff fried with beef tallow?
Thu Mar 26, 2026, 10:42 PM
Thursday

because MAHA thinks beef tallow is healthier than seed oil

mwmisses4289

(4,142 posts)
30. Beef tallow, lard, bacon drippings, sheep fat.
Thu Mar 26, 2026, 10:58 PM
Thursday

Beef tallow may be healthier for some, but for those with alpha gal, it's could be potentially deadly.

DBoon

(24,980 posts)
31. I'm seeing "healthy" restaurants touting their use of beef tallow
Thu Mar 26, 2026, 11:09 PM
Thursday

"potentially deadly" is not something I associate with healthy eating

Somehow the RFK Jr. people have been lead to believe seed oils are unhealthy and beef tallow is good

ON EDIT: And these are the places that make a big deal out of "gluten free"

Warpy

(114,603 posts)
13. What makes this so unusual is that it appears to be an infectious allergy
Thu Mar 26, 2026, 07:13 PM
Thursday

It isn't transmitted from person to person, it requires a tick as a vector. Once it develops, it turns into an often deadly allergy to mammal meat. Birds, eggs, fish, and veggies can be eaten safely, but those steaks and roasts are out, along with breakfast and lunch meats.

The good news is hat the allergy can disappear in some people. The bad news are that it often takes years to go away and in a significant number of people, it never goes away.

I suppose I'm a little surprised by how fast it has spread from the southern plains to the east, even though such a spread was predicted. I guess ticks have been hitching a lot of rides on vehicles.

It's still fairly rare. Just know the danger signs of severe allergic reaction, anaphylaxis or anaphylactic shock. Yes, I want you to look it up.

Bottom line: if you get it, you won't starve. Some substitutes, like chicken and apple and chicken sausage, can be great. You will get enough B-12. Greens will give you plenty of iron. It might even go away, allowing you a ham sandwich, beef steak, or bison burger a few years down the road. Just be aware that this is out there, what the severe symptoms are, and what to do if the worst happens.

wnylib

(25,979 posts)
17. No luncheon meat? What about sliced deli turkey
Thu Mar 26, 2026, 08:31 PM
Thursday

and things made with turkey, e.g. sausage and pepperoni?

wnylib

(25,979 posts)
20. Good grief. Hope I never have to deal with this allergy.
Thu Mar 26, 2026, 08:55 PM
Thursday

I already have a list of foods that I can't eat due to allergies. Then there are others that I limit or avoid due to watching cholesterol and solid fat intake. Then there are some that I avoid or eat in very small amounts on rare occasions due to interactions with one of my meds.

Among my food allergies are some calcium rich veggies, so I count on milk and low fat cheese for calcium.

I am at least familiar with the signs of anaphylaxis, having experienced it twice, both times caused by allergists who were skeptical of my warning to them about some of my allergen reactions. Yes, I immediately wrote off both doctors as incompetent -- after I received epinephrine shots and recovered.


highplainsdem

(62,066 posts)
22. Sorry you have to avoid so many foods. I often limit wheat as much as possible because I'll get
Thu Mar 26, 2026, 09:17 PM
Thursday

mild allergy symptoms from that, but they're respiratory symptoms and pretty mild - sneezing and watery eyes (I'll notice tree pollen a lot more if I've been eating wheat). I'll sometimes have pizza anyway, and I couldn't resist the carrot cake at my nearest grocery store's very good bakery this week, but I'll often go months without eating wheat...and then go back to eating it again until the allergy symptoms are just too annoying.

I've never had anaphylaxis. It sounds terrifying.

wnylib

(25,979 posts)
24. The first time I experienced anaphylaxis, I was too spaced out from it
Thu Mar 26, 2026, 09:37 PM
Thursday

and too unfamiliar with it to know what was happening. The doctor had left me alone in a cubicle after injecting me with 60 test allergens at once. I felt pain in my ear lobes and was dizzy, like I might faint.

Fortunately, an acquaintance of mine worked in that office and poked her head in the doorway of the cubicle to say hello. When she saw me, she immediately yelled out for the doc. I had no idea why everyone was rushing around, prepping shots, checking my pulse, etc.

Later my friend told me l that my ear lobes were swollen about 3 times their normal size and had turned deep purple. My arms, from shoulders to wrists were puffed up like balloons and had purple streaks running the full length.

I had to wait several hours in the office before leaving to be sure that the episode was completely over. I got jittery and felt hyped up from the epi shots because the doc ordered 3 instead of the usual 2. So they gave me some crackers to munch on.





highplainsdem

(62,066 posts)
25. The doctor left you alone after injecting you with 60 test allergens at once? That sounds like
Thu Mar 26, 2026, 10:30 PM
Thursday

malpractice. Thank God your acquaintance there stopped by soon after that and realized it was an emergency.

wnylib

(25,979 posts)
34. The office set up was like a mill. There were several
Fri Mar 27, 2026, 04:22 AM
Friday

cubicles where patients waited after being injected. The routine was to start with the doc for an initial interview. Then he ordered the types of tests. A nurse injected the allergens being tested and said she would be back in 15 minutes to check the results. Then she moved on to the next cubicle.

I was 35 when the tests were done and had never been fully tested before. Since childhood, I'd had numerous "colds" every year and bouts of abdominal cramps, which were assumed to be flu, plus frequent bouts of tonsillitis. So I had a tonsillectomy at age 6. But I still got sick often. As an adult, none of the GPs I'd seen had considered allergies or asthma when I got bronchitis so often.

My husband insisted that I get fully tested after a scarey reaction to a pet rabbit.

The allergist was visibly skeptical of the variety of symptoms and substances that I told him about in the initial interview. I think he thought that I was a hypochondriac.

After the epi shots took effect, the doc said that I had reacted positively to all but 4 of the allergens. But how could he know with my entire arms swollen instead of little bumps as positive reactions?

So I found another allergist who tested each substance individually, with a nurse at my side throughout the tests.

My childhood illnesses turned out to be allergies to our real pine Christmas tree each year, my wool blanket and feather pillow, my mother's pet parakeet, and the pollens in our backyard flower and vegetable gardens. Plus tree and grass pollens, fungi (mushrooms), several foods, and some meds.

Avoiding the worst allergens is automatic routine now. Some food reactions are so mild that I can eat them in small amounts. I became desensitized to some allergens after treatments, and keep antihistamines on hand for pollen seasons. So I rarely get any reactions any more.







highplainsdem

(62,066 posts)
35. Thanks for explaining! I still think that first allergist you saw was incredibly irresponsible, putting
Fri Mar 27, 2026, 08:49 PM
Friday

you at risk that way, and I wonder how many other patients he endangered.

Thank God the next allergist you saw was much more competent.

I'm glad you've been able to manage your allergies much better now.

I made a mistake myself thinking my wheat allergy was mild enough I probably wouldn't regret eating about half of that small carrot cake over a few days. Told myself it had to have a lot less wheat than most cakes, simply because of the other ingredients (this is really good, really rich carrot cake, with wonderful cream cheese frosting). Now I don't know whether a lot of coughing and sneezing I've been dealing with today are the allergy or a cold or some other respiratory virus I might've caught. Sigh...

But I just searched for and found a gluten-free version.
https://www.bonappetit.com/story/gluten-free-carrot-cake

wnylib

(25,979 posts)
37. I don't blame you for trying the carrot cake.
Fri Mar 27, 2026, 09:47 PM
Friday

I love carrot cake and fortunately, can eat it with no problems.

Have you been tested for wheat allergy? Wheat is hard to avoid, although there are a lot of no gluten, wheat free products now.

I've learned that, although I can't eat any egg dishes like scrambled, boiled, or fried eggs because of the allergy to egg whites, I can eat a few things, like cake or cookies made with eggs, so long as there are only one or two eggs in them. The other ingredients do dilute the effect of the egg whites for me. But I can't eat angel food cakes-- too many egg whites.

Also, although I can't eat fresh tomatoes, e.g. on a sandwich or in a salad, I can eat cooked tomatoes like in pizza or spaghetti sauce. Cooking changes the protein structure enough so that cooked tomatoes sneak right past my over zealous immune system.

It took years of trial and error to learn what is safe and in what amounts or combinations.

One way to tell the difference between an allergy and a cold is to check your temperature. Allergies do not raise the temp like an infection does. Also, nasal mucous color is white or clear with allergies. It is green, sometimes gray, with an infection like a cold.

Good luck on avoiding wheat.







highplainsdem

(62,066 posts)
39. No allergy test, but I started getting respiratory symptoms from eating wheat again
Fri Mar 27, 2026, 10:57 PM
Friday

after having given it up for quite a while the first time, after hearing about the book Wheat Belly and being impressed by what I read about the benefits of a wheat-free diet. I did NOT expect to find myself sneezing and coughing after going back to eating wheat again, since it hadn't had that effect before. But I'd read that other people who'd tried to go back to eating wheat had more trouble with it. I had noticed, the first time I went wheat-free, that I was no longer getting watery eyes from being outdoors when the tree pollen count was especially high, so I guess I shouldn't have been completely surprised to get respiratory symptoms when I ate wheat again.

wnylib

(25,979 posts)
41. The reason I asked if you had been tested is that
Fri Mar 27, 2026, 11:41 PM
Friday

Last edited Sat Mar 28, 2026, 07:41 AM - Edit history (1)

some other ingredients in products that use wheat can cause allergies, e.g. yeast in breads, bagels, and some doughnuts. With cakes, eggs, milk, or some spices can cause allergies.

However, if you are allergic to a food, you will notice symptoms if you try eating it after an interval without it. So maybe that is what happened when you ate the cake.

I tested positive for a peanut allergy, which surprised me because I had never noticed a reaction to peanuts. But I had to avoid them after I started one of my meds because peanuts, peanut butter, and peanut oil nullify the effect of my med. After a few years of avoiding peanuts, I accidentally bit into a peanut cookie that an employee had brought to work because I mistook it for an oatmeal cookie. Immediately I started coughing, then went into a full blown asthma attack.

I wonder if it's a specific type of wheat that you are allergic to, e.g. the wheat used in breads and cakes. What about pasta, which is made with semolina and duram wheat? Or dark rye or pumpernickel bread? Most of those have some white wheat flour in them, but a few are made without it.

Interesting that there is a connection between tree pollens and reactions when you eat wheat. Some allergen effects are cumulative, meaning that, in small amounts by themselves, they are fairly harmless, but when you are exposed to another allergen, too, the immune system decides that's a bridge too far and reacts more strongly to having both exposures than to just one.

Tree pollens are a common allergy and hard to avoid in spring.












mwmisses4289

(4,142 posts)
23. Just make sure you check ingredients, as anyone living with allergies know to do.
Thu Mar 26, 2026, 09:28 PM
Thursday

Some sausages made with chicken may also contain beef or pork. Same with lunch meat.
It does get easier to deal with over time.

buzzycrumbhunger

(1,930 posts)
29. Blargh--ticks
Thu Mar 26, 2026, 10:55 PM
Thursday

I agree the planet has it in for us, probably with good reason.

You might be surprised to find that there are vegan analogues to pretty much any kind of meat, though I can’t swear to beef because that’s not something I was ever fond of and haven’t tried making. Ham, turkey, and chicken, though? Surprisingly easy! (I think these all came from It Doesn’t Taste Like Chicken, if you’re interested. Pinterest has lots more.) Might be an option if this is something you feel deprived of.



Bayard

(29,636 posts)
32. Never heard of it
Fri Mar 27, 2026, 12:49 AM
Friday

The little bitty ticks are popping up here now since its warming up. I've picked several off already, but I spend a lot of time outside.

highplainsdem

(62,066 posts)
36. I found a Cleveland Clinic Journal of Medicine page with a map showing where AGS is most common. Link:
Fri Mar 27, 2026, 09:04 PM
Friday
https://www.ccjm.org/content/92/5/311/tab-figures-data

See figure 2 there.



The largest area for AGS being found most often is that dark blue section covering much of Missouri and Arkansas and smaller adjacent sections of Kansas and Oklahoma. My two Missouri relatives who caught AGS live approximately in the center of that section.

mackdaddy

(1,972 posts)
40. I have had Alpha Gal for a couple of years now.
Fri Mar 27, 2026, 11:31 PM
Friday

I am in SE Ohio not far from Athens. I live in a rural area and walk with the dogs every day so I have a lot of tick exposure. The tiny ticks are Deer ticks an carry Lyme and Ehrlichiosis which are both microbe diseases and both of my dogs have had both diseases. A slightly larger tick with a single dot on its back is called the "Lone Star" tick and is what can cause the Alpha Gal allergy. This is a chemical it picks up from other mammals and injects you with when they later bite humans.
My main symptom was a cramping after a couple of bites of a hamburger or sour cream dish. They have a blood test to see how reactive you are to this. Basically I can have an allergic reaction to any Mammal product, meat, dairy or even gelatin. I have to be careful of some medicine capsules that are made from gelatin. I have never had an extreme reaction but I do carry an eppi pen now.

We always had normal 'dog' ticks, but these new species just showed up in the last 5 or six years.

I have to turn off commercials for sizzling steak or bacon. I really miss them. Chicken, turkey, eggs, and fish are about it for meat and Almond milk helps replace dairy.

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