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Rocknation

(44,954 posts)
Sat Nov 29, 2025, 02:00 AM Saturday

Repeated Infusions and MRIs -- "symptoms" of an Alzheimer's diagnosis?

Last edited Tue Dec 2, 2025, 08:24 PM - Edit history (13)

FDA.gov (August 2025): FDA to recommend additional, earlier MRI monitoring for patients with Alzheimer’s disease taking Leqembi (lecanemab)

The earlier monitoring can identify individuals with amyloid-related imaging abnormalities with edema (ARIA-E), which is characterized by brain swelling or fluid buildup. ARIA-E is usually asymptomatic, although serious and life-threatening events, including seizure and status epilepticus, can occur and there have been deaths...

We are requiring the prescribing information of Leqembi (lecanemab) to include an earlier monitoring MRI between the 2nd and 3rd infusion...To identify patients experiencing ARIA-E, ...(We also) recommend...(that)...(p)atients should...obtain (a)...MRI...within one year before starting treatment...for a baseline comparison...and MRI imaging BEFORE the 3rd, 5th,7th, and 11th infusions...


Facebook, November 19, 2025: Is Trump being treated...with...experimental... Alzheimer's drugs lecanemab (Leqembi)...(or)...donanemab (Kisunla)? The(y)...are designed to slow disease progression by clearing amyloid plaques from the brain in the early stages of the disease...(Both drugs) are administered via IV infusion and require close...(MRI) monitoring due to risks like brain swelling and bleeding. Doctors say the bruises on his hand noticed recently are consistent with such infusions. Trump also revealed recently that his most recent medical exam included an MRI...(but) said he did not know why the MRI was performed.

I'm not an expert on any of this medical information, but what I have read on reliable medical sites checks out. I'm not an expert on any of this medical information, but what I have read on reliable medical sites checks out. I also don't know if there are other conditions that also require infusions and monitoring by MRI. I'm just asking questions here.


Trump actually HAVING Alzheimer's would explain his monthly annual physical exams, excessive infusions, multiple MRIs -- and what the FDA describes as "loss of memory, problem solving, and ability to think clearly which can interfere with daily life."

President Ronald Regan had Alzheimer's; Trump claimed that President Joe Biden did. But the bottom line is, if Trump DEFINITELY has Alzheimer's, the world has the right to know it -- and we now definitely have the means to oust him. The drugs in question show promise only in slowing the progression of the disease, not in halting or eliminating it. In that respect, early stage Alzheimer's is no different than from being a little bit pregnant.

Rocknation
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Repeated Infusions and MRIs -- "symptoms" of an Alzheimer's diagnosis? (Original Post) Rocknation Saturday OP
It seems like Vascular Dementia to me CountAllVotes Saturday #1
So sorry you and your husband had to go through this, CountAllVotes Grim Chieftain Saturday #3
It has been a living hell CountAllVotes Saturday #5
Bless your heart Grim Chieftain Saturday #7
The Doors - The End CountAllVotes Saturday #10
He can't have ARIA-E Jerry2144 Saturday #2
The Infusion cost is $26,000 a year. Then add on MRI and other $$$$$ Cattledog Saturday #4
Our family is Living with snowybirdie Saturday #6
I'm convinced he's either had a stroke or has something Ilsa Saturday #8
This is interesting and lines up but is also very disappointing BannonsLiver Saturday #9

CountAllVotes

(22,041 posts)
1. It seems like Vascular Dementia to me
Sat Nov 29, 2025, 02:09 AM
Saturday

It involves veins that they seal off and reroute the blood to nearby healthier veins. This could help for awhile but ...

It turns into what I had to deal with, namely vascular dementia which is what my husband died from in 2022.

It was quick and dirty in his case albeit it was going on for quite awhile as he was good at hiding the symptoms. However, that caught up with and he was gone three months after the DX. Sad.

It is a horrible way to die as the individual that is affected is having delusions and is gone in the head for the most part as they revert to childlike behaviors that are other inexplicable when they reach THE END of this living hell.

& recommend.

CountAllVotes

(22,041 posts)
5. It has been a living hell
Sat Nov 29, 2025, 06:08 AM
Saturday

Lots of things are now GONE, gone for good.

It was so horrible, I will never get over it.

It has been 3-1/2 years since he died and I remember the name of the procedure done on an out patient basis. It is called "VENASEAL". They did one leg at a time.

https://www.medtronic.com/en-us/l/patients/treatments-therapies/varicose-vein-treatments/venaseal-procedure.html

After that, the strokes became more frequent along with the falls, that is part of it too.

In the end he was a frightened mess and I was no better not knowing what to do. I'd never heard of "vascular dementia" until it was part of my sad life and he was so confused ... it was a blessing when he died really.



Grim Chieftain

(1,022 posts)
7. Bless your heart
Sat Nov 29, 2025, 10:13 AM
Saturday

I cried reading this. No one should have to endure what you and your husband went through. I hope you have friends and loved ones who can be a source of comfort and support. You are in my thoughts and prayers, dear lady.

snowybirdie

(6,502 posts)
6. Our family is Living with
Sat Nov 29, 2025, 06:58 AM
Saturday

this decision of a loved one taking these new drugs or not. We choose not to. The rate of improvement is less than 30%. If he's taking them, they won't help much and the multiple MRIs make these drugs not really worth it, especially for a 79 year old.

Ilsa

(63,672 posts)
8. I'm convinced he's either had a stroke or has something
Sat Nov 29, 2025, 10:34 AM
Saturday

like Bell's palsy. A picture of the Slobfather seated with Malignia from several days ago was posted on X or BlueSky or Instagram. The right side of his face is droopier than I've ever seen before. I wish I could find the pic.

BannonsLiver

(20,147 posts)
9. This is interesting and lines up but is also very disappointing
Sat Nov 29, 2025, 10:38 AM
Saturday

I was hoping it was something that progressed a little more quickly.

On edit: I’m not sure it accounts for the cankles and his inability to stand for more than a few minutes at a time. He could be dealing with multiple issues, if we’re lucky.

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