The Nobel Prize in medicine goes to 3 scientists for work on the human immune system

https://apnews.com/article/nobel-prize-medicine-a68cf8a3b930570630168a949d277cde

The Nobel Prize in medicine goes to 3 scientists for work on the human immune system
By KOSTYA MANENKOV, LAURAN NEERGAARD and LINDSEY WASSON
Updated 8:22 AM CDT, October 6, 2025

STOCKHOLM (AP) — Mary E. Brunkow, Fred Ramsdell and Dr. Shimon Sakaguchi won the Nobel Prize in medicine Monday for their discoveries concerning peripheral immune tolerance.

Brunkow, 64, is a senior program manager at the Institute for Systems Biology in Seattle. Ramsdell, 64, is a scientific adviser for Sonoma Biotherapeutics in San Francisco. Sakaguchi, 74, is a distinguished professor at the Immunology Frontier Research Center at Osaka University in Japan.

“Their discoveries have been decisive for our understanding of how the immune system functions and why we do not all develop serious autoimmune diseases,” Olle Kämpe, chair of the Nobel Committee, said.

The award, officially known as the Nobel Prize in Physiology or Medicine, is the first of the 2025 Nobel Prize announcements and was announced by a panel at the Karolinska Institute in Stockholm.

The physics prize will be announced on Tuesday, chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be announced Friday and the Nobel Memorial Prize in economics Oct. 13.

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